AmpliSens® Leukosis-Quantum M-bcr-FRT
Cat. Number: TR-O1(RG,iQ,Mx,A)-CE
AmpliSens® Leucosis Quantum M-bcr-FRT PCR kit is an in vitro nucleic acid amplification test for qualitative and quantitative detection of the bcr-abl chimeric gene (M-bcr variant) mRNA and abl gene mRNA in the clinical materials (peripheral blood, bone marrow) by using real-time hybridization-fluorescence detection.
AmpliSens® Leucosis Quantum M-bcr-FRT PCR kit can be used for screening detection of CML (chronic myelogenous leukemia) associated with M-bcr-abl chromosomal rearrangement, confirmation of CML diagnosis, and monitoring of the minimal residual disease (MRD) and therapy efficiency.
RNA extraction and reverse transcription steps are included.
Adapted for:
- Rotor-Gene 3000/6000 (Corbett Research, Australia)
- iCycler iQ (Bio-Rad, USA)
- Mx3000P (Stratagene, USA)
- ABIPrism (Applied Biosystems, USA)
In its absence, the product is not intended for medical purposes in the territory of the Russian Federation.
**RUO- the product is not intended for medical purposes in the territory of the Russian Federation
PCR is the basic method when working with nucleic acids, allows you to multiply the number of copies of the target DNA site and determine the initial concentration of the desired sequences during real-time analysis time.
In addition, this method has been widely used in molecular diagnostics for the determination of pathogens infectious diseases and predispositions to hereditary diseases. Cooling and heating of samples with the necessary frequency and duration required for conducting PCR, provided by special devices – amplifiers (thermal cyclers).